The minimal cardiopulmonary bypass (mini-CPB) circuit, a closed system with neither
cardiotomy suction nor an open venous reservoir and thus no air–blood interface, reportedly
reduces blood loss and inflammatory reactions associated with coronary bypass surgery.
We evaluated the inflammatory reactions in patients in whom coronary bypass operations
were performed with conventional CPB or mini-CPB (n= 15 each). Interleukin (IL)-6, IL-8,
and neutrophil elastase levels; the neutrophil count; and the C-reactive protein value were …

Objectives: A mini-cardiopulmonary bypass (CPB) circuit, consisting of a closed system with
neither cardiotomy suction nor a venous reservoir to prevent air-blood interface, is reported
to reduce blood loss and inflammatory reactions in coronary bypass surgery. In this study,
we evaluated inflammatory reactions induced by mini-and conventional CPB. Methods: The
conventional and mini-CPB systems were used in 10 patients each. Inflammatory cytokines
(IL-6 and-8), neutrophil elastase (NE), and alveolar surfactant protein were measured before …